These decks aren't guaranteed to give you a win. But they definitely are worth getting tried out.
LoR: The 3 Best Off-Meta Decks For Patch 4.10
The new Legends of Runeterra patch just rolled out and I'm here to bring you some new goodies with low play rate. Beware, because low play rate statistics aren't always reliable.

I gotta be honest. I don't like playing meta. It's far more interesting to try out some decks who aren't played by everyone.
What are the advantages you may ask?
Well first of all, the enemies don't really know what you are doing and that means you can catch them off guard. When they understand your win condition, it's most likely too late.
Also, there won't be meta decks without players trying out new things. Who knows, maybe those decks are just insanely OP but no-one knows them?
I mean, I hit Master-Tier within a few weeks of playing this game, just because I abused some off-meta decks.
One thing is for sure: You can't balance such a complex game like Legends of Runeterra perfectly. There will always be something broken which no-one has thought of yet...
But enough about that talk, let's dive right in!
LeBlanc (NX / FR)

For what does Noxus stand? FOR GLORY!!! Yeah, and also for units with extremely strong power, but bad defense.
So hear me out: There's a landmark which is called "Temple Of True Ice", which, when you summon an ally, grows its health to its power.
Suddenly, you don't have a 5/1 Trimaran Gloryseeker at 2 cost, but instead a 5/5 one. Same goes for LeBlanc and with the Wrathful Rider you even have an 8/8 with Challenger at 5 cost.
Also, we have Omen Hawk in the deck, to give your units even more health and to deal with those Elusive units in the early game.
So it should be pretty easy for you to activate your Reputation and get LeBlanc leveled.
I can tell you, a board with 4 Trimaran Gloreyseekers at 5/5 and Rally at round 6 is pretty strong.

This deck has a win rate of 83% in High Dia / Masters. It's only 24 games played in total, but maybe it could be the next new meta?
Deckcode: CEDQCAIBCYAQKAYTAEDAABQBA4AQWAIIAEJQGAIDCAPSCAYEAMCAQDYDAEAQGCYBAMBQSAIIAMGACAIBAMJQ
Fizz / Yuumi (BW / MT)

Well, you know that Fizz can’t really be targeted by spells, right? And on top of that, he gets Elusive.
Here's a different deck for you. It relies on Fizz to basically be your solo carry with Yuumi on top of him.
With Pool Shark you are trying to force Fizz, while Buhru Leader enables Fizz to get an extra attack.
It's a pretty forward deck. Your goal is to just make Fizz as strong as possible and strike through the enemy deck with Elusive.
Cosmic Youngling allows you to stall for that. And you can even make Fizz a dragon with Draconic Bands!

This deck has a win rate of 85% in High Dia / Masters with 17 out of 20 games won.
Deckcode:
CQDQCBIKDUAQKCIIAEDAMCIBA4EQGAQCAYES4AQGBEVTIBIDBERS2M2VMIAACAIGBEQQ
Renekton / Leona (MT / SH)

Renekton and Leona are an unlikely duo, but they're here to bring some sun into the desert of your LP gains.
This deck is based on Leonas Ability to single out targets, while stunning other ones.
General Of The Dunes is essential, to give enemies Vulnerable. Because you basically can play the entire enemy board how you want them to play, you can easily level up Renekton and destroy their Nexus with Overwhelm.

This deck has a win rate of 91% in high dia / masters. It has 21 out of 23 games won, so please look at those statistics with a grain of salt.
Deckcode:
CMCACBAJBUAQMCJKAEEAOBIGAMERUHBDFQ3FQBABAMEROAIIBENQCCAHAQBQIBZNINWQCAIDBFKQ
I hope these decks gave you some cool new alternatives to play, instead of the same old boring meta decks.